Liquid Biopsy that Looks Deeper
Mesa Alta Research is pioneering a radical new approach to liquid biopsy—using apheresis to capture circulating cell-free DNA from the bloodstream in unprecedented amounts, for the utmost sensitivity in MRD and MCED testing.
cfDNA Apheresis
Our proprietary Plasma-Sieve apheresis device and methods leverage a high-affinity adsorption matrix to selectively capture and purify circulating cell-free DNA (cfDNA) directly from plasma with yields in micrograms, not nanograms.
Superior Sensitivity
Microgram-scale yields of cfDNA enable us to construct Ultra-Deep cfDNA Libraries for next-gen sequencing panels in MCED testing while also interrogating vastly larger cfDNA inputs by digital PCR in tumor-informed MRD assays, improving the analytical limits of detection (LOD) for cfDNA tumor markers by 100- to 1000-fold.
Clinical Impact
A new frontier of sensitivity in assays for minimal/microscopic residual disease (MRD) and in multi-cancer early detection (MCED) tests, where every cfDNA fragment is critical.
Connect with Our Research Team
For collaboration inquiries or technical documentation, please contact us at our Albuquerque headquarters.
5901 INDIAN SCHOOL ROAD NE
ALBUQUERQUE, NEW MEXICO 87110
Sandia Mountains, Albuquerque, New Mexico